L-Arginine, Nitric Oxide, & Fertility

L-Arginine is an amino acid present in human proteins. L-Arginine’s primary function involves the metabolism of protein and nitrogen. Moreover, recent Nobel-Prize winning research has confirmed arginine’s role as a support mechanism for circulatory and cardiovascular health. L-Arginine is a key precursor to nitric oxide (NO), a small molecule that is responsible for relaxing blood vessels and promoting circulation.

L-Arginine plays several physiological roles, assisting in healing, helping divest ammonia from the body, supporting immune function, and promoting endometrial and cervical secretion. L-Arginine is required by the body to synthesize nitric oxide (NO), and plays key roles in the cardiovascular, immune, and reproductive systems. Nitric oxide supports blood vessel dilation, which may help circulation and vascular relaxation. Nitric oxide is formed from arginine via the enzyme nitric oxide synthase or synthasetase (NOS). One of its functions is to regulate smooth muscle contraction.

How L-Arginine & NO Work to Promote Fertility

L-Arginine, Nitric Oxide and FertileCM: Toward Enhancing Female Fertility

FertileCM is a dietary supplement designed to promote the presence of cervical mucus by supporting the production of nitric oxide (NO). Nitric oxide is produced naturally by the body and is important for numerous bodily functions. Among these, nitric oxide dilates blood vessels and helps promote blood flow to the uterus, ovaries, and genitals. The effect of this process includes an increase of endocervical secretions during the ovulatory phase in women. In one key study, "nitric oxide (NO) administration markedly increased cervical secretion" for women taking supplementation in the test group, "while no changes in cervical secretion were seen in the control group."

In one key study, "nitric oxide (NO) administration markedly increased cervical secretion" for women taking supplementation in the test group, "while no changes in cervical secretion were seen in the control group."

In addition, other resarech studies indicate that FertileCM, by providing a key precursor for nitric oxide (NO), may increase vascular dilatation, blood flow, and muscular relaxation around the vagina, thereby enhancing libido and improving sensation to sexual stimulation.

Conclusion: Research demonstrates that the amino acid L-arginine (contained in the FertileCM formula) may safely increase cervical mucus, support endometrial secretions and a healthy uterus during implantation time, and enhance female sexual arousal.

		To read more about how FertileCM works to promote fertility and increase your odds of conceiving, click here.
		To learn more about the purpose of cervical mucus in fertility - and its role as a natural fertility sign in predicting ovulation - click here.
		To read more about the function of each ingredient in the FertileCM formula, click here.

Nobel Prize Awarded for Nitric Oxide

Nobel Prize Awarded to Scientists for Nitric Oxide Discoveries

Nitric oxide was named "Molecule of the Year" in 1992 by the journal Science, but it took another 6 years for those responsible for the major discoveries surrounding it to win the Nobel Prize.

The discovery of nitric oxide's signaling role in the cardiovascular and nervous systems is now nearly 20 years old, but its clinical use is only beginning. Dr Furchgott, a distinguished professor of pharmacology at the State University of New York (SUNY) at Brooklyn, began the studies that led to the identification of nitric oxide as a biological agent in 1980. He concluded that endothelial cells produce an unknown signal molecule that makes vascular smooth muscle cells relax.

In unrelated experiments, Dr Murad, now chairman of the integrative biology department at the University of Texas Medical School at Houston, was analyzing how nitroglycerin works. In 1977, while at the University of Virginia, he found that nitrates release nitric oxide, which relaxes smooth muscle cells, resulting in vasodilation. He was fascinated that the colorless, odorless gas could act as a signaling molecule.

Dr Ignarro, now a professor of pharmacology at UCLA School of Medicine in Los Angeles, California, through a series of analyses concluded in 1986 that EDRF was identical to nitric oxide. His work, done independently and together with that of Dr Furchgott, prompted an increase in research activities in many areas of the world.

What the Nobel prize recognized was the scientists' dogged efforts to prove that nitric oxide, an endogenous gas and also a free radical, could have this kind of crucial biological effect. Research has proven the crucial role the gas plays in such fundamental biological processes as regulation of blood pressure, functioning and malfunctioning of the immune system, and activation of mechanisms in the central nervous system.

Current studies and clinical applications based on Nobel prize winning research include aspects of female fertility, including nitric oxide's impact on increasing cervical mucus secretions during a woman's fertile time, as well as promoting enodmetrial secretions to assist in supporting the development of a healthy endometrial lining. L-arginine, a nitric oxide precursor, has also been demonstrated to support female sexual function and arousal.

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